Omega-3 Fatty Acid Concentration Linked to Cognitive Function – Consumer Health News


WEDNESDAY, Oct. 5, 2022 (HealthDay News) — In a mostly middle-aged cohort, higher concentrations of omega-3 fatty acids are associated with better brain structure and better cognitive function, according to a study published online. on October 5 in Neurology.

Claudia L. Satizabal, Ph.D., of UT Health San Antonio, and colleagues examined the cross-sectional association of omega-3 fatty acid concentrations in red blood cells with magnetic resonance imaging and cognitive markers of brain aging in a community sample of predominantly middle-aged adults. Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) concentrations were measured and the omega-3 index was calculated as DHA + EPA.

Data were included for 2183 participants without dementia or stroke (22% APOE ε4 carriers). The researchers found that a higher omega-3 index was associated with larger hippocampal volumes and better abstract reasoning in multivariate models. Similar results were observed for DHA and EPA concentrations separately. Associations have been observed between higher DHA concentrations or an omega-3 index and larger hippocampal volumes in APOE ε4 non-carriers, whereas in APOE ε4 transporters, higher concentrations of EPA were linked to better abstract reasoning. In APOE Carriers of ε4 only, higher levels of all omega-3 predictors were linked to lower white matter hyperintensity load.

“These findings need to be confirmed by further research, but it’s exciting that omega-3 levels may play a role in improving cognitive resilience, even in middle-aged people,” Satizabal said in a statement.

Several authors revealed links with the pharmaceutical industry.

Abstract/Full text (subscription or payment may be required)

Previous Learn how to improve your public speaking skills at a Toastmasters Open House in Oakhurst on Thursday, October 20, 2022
Next NYC steps up safety strategy at 'toughest' schools